© 2023 NIVB
Masaryk University
Evolution of RNA viruses in trypanosomatids: new insights from the analysis of Sauroleishmania
Klocek, D., Grybchuk, D., Ticha, L., Votypka, J., Volf, P., Kostygov, A. Y., & Yurchenko, V. (2023). Parasitol Res, 122(10), 2279-2286.
Translation machinery captured in motion
Zafar, H., Hassan, A. H., & Demo, G. (2023). Wiley Interdiscip Rev RNA, 14(5), e1792.
Stealthy Player in Lipid Experiments? EDTA Binding to Phosphatidylcholine Membranes Probed by Simulations and Monolayer Experiments.
Vazdar, K., Tempra, C., Olzynska, A., Biriukov, D., Cwiklik, L., & Vazdar, M. (2023). J Phys Chem B, 127(24), 5462-5469.
Escherichia coli from biopsies differ in virulence genes between patients with colorectal neoplasia and healthy controls.
Bosak, J., Kohoutova, D., Hrala, M., Krenova, J., Moravkova, P., Rejchrt, S., Bures, J., & Smajs, D. (2023). Front Microbiol, 14, 1141619.
Complete genome sequences of five Escherichia coli strains with probiotic attributes.
Fedrova, P., Hrala, M., Tom, N., Micenkova, L., Nascimento, A. M. A., Bosak, J., & Smajs, D. (2023). Microbiol Resour Announc, 12(9), e0036323.
Novel Antimicrobial Genetic Elements in Methicillin-Resistant Macrococcus armenti
Keller, J. E., Schwendener, S., Novakova, D., Pantucek, R., & Perreten, V. (2023). Microb Drug Resist, 29(2), 65-68.
Staphylococcus aureus Prophage-Encoded Protein Causes Abortive Infection and Provides Population Immunity against Kayviruses
Kuntova, L., Maslanova, I., Oborilova, R., Simeckova, H., Finstrlova, A., Bardy, P., Siborova, M., Troianovska, L., Botka, T., Gintar, P., Sedo, O., Farka, Z., Doskar, J., & Pantucek, R. (2023). mBio, 14(2), e0249022
Staphylococcus brunensis sp. nov. isolated from human clinical specimens with a staphylococcal cassette chromosome-related genomic island outside of the rlmH gene bearing the ccrDE recombinase gene complex
Kovarovic, V., Finstrlova, A., Sedlacek, I., Petras, P., Svec, P., Maslanova, I., Neumann-Schaal, M., Sedo, O., Botka, T., Stankova, E., Doskar, J., & Pantucek, R. (2023). Microbiol Spectr, e0134223.
Charles University
The role of sand flies as vectors of viruses other than phleboviruses
Jancarova, M., Polanska, N., Volf, P., & Dvorak, V. (2023). J Gen Virol, 104(4). https://doi.org/10.1099/jgv.0.001837
Experimental feeding of Sergentomyia minuta on reptiles and mammals: comparison with Phlebotomus papatasi
Ticha, L., Volfova, V., Mendoza-Roldan, J. A., Bezerra-Santos, M. A., Maia, C., Sadlova, J., Otranto, D., & Volf, P. (2023). Parasite Vectors, 16(1), 126.
Characterisation of the antiviral RNA interference response to Toscana virus in sand fly cells
Alexander, A. J. T., Salvemini, M., Sreenu, V. B., Hughes, J., Telleria, E. L., Ratinier, M., Arnaud, F., Volf, P., Brennan, B., Varjak, M., & Kohl, A. (2023). PLoS Pathog, 19(3), e1011283.
Enhanced transmissibility, infectivity, and immune resistance of the SARS-CoV-2 omicron XBB.1.5 variant
Uriu, K., Ito, J., Zahradnik, J., Fujita, S., Kosugi, Y., Schreiber, G., Genotype to Phenotype Japan, C., & Sato, K. (2023). Lancet Infect Dis, 23(3), 280-281.
Virological characteristics of the SARS-CoV-2 omicron XBB.1.16 variant.
Yamasoba, D., Uriu, K., Plianchaisuk, A., Kosugi, Y., Pan, L., Zahradnik, J., Genotype to Phenotype Japan, C., Ito, J., & Sato, K. (2023). Lancet Infect Dis, 23(6), 655-656
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant.
Ito, J., Suzuki, R., Uriu, K., Itakura, Y., Zahradnik, J., Kimura, K. T., Deguchi, S., Wang, L., Lytras, S., Tamura, T., Kida, I., Nasser, H., Shofa, M., Begum, M. M., Tsuda, M., Oda, Y., Suzuki, T., Sasaki, J., Sasaki-Tabata, K., . . Sato, K. (2023). Nat Commun, 14(1), 2671.
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
Tamura, T., Ito, J., Uriu, K., Zahradnik, J., Kida, I., Anraku, Y., Nasser, H., Shofa, M., Oda, Y., Lytras, S., Nao, N., Itakura, Y., Deguchi, S., Suzuki, R., Wang, L., Begum, M. M., Kita, S., Yajima, H., Sasaki, J., . . Sato, K. (2023). Nat Commun, 14(1), 2800.
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips
Dvorak, J., Novakova, J., Kraftova, L., Studentova, V., Matejovic, M., Radej, J., Karvunidis, T., Horak, J., Kralovcova, M., Hrabak, J., Kalaninova, Z., Volny, M., Novak, P., & Pompach, P. (2023). Clin Proteomics, 20(1), 20.
Polyclonal Spread of Fosfomycin Resistance among Carbapenemase-Producing Members of the Enterobacterales in the Czech Republic.
Mattioni Marchetti, V., Kraftova, L., Finianos, M., Sourenian, T., Hrabak, J., & Bitar, I. (2023). Microbiol Spectr, 11(3), e0009523.
Implication of different replicons in the spread of the VIM-1-encoding integron, In110, in Enterobacterales from Czech hospitals
Bitar, I., Papagiannitsis, C. C., Kraftova, L., Marchetti, V. M., Petinaki, E., Finianos, M., Chudejova, K., Zemlickova, H., & Hrabak, J. (2022). Front Microbiol, 13, 993240.
. Improving the antimicrobial activity of old antibacterial drug mafenide: Schiff bases and their bioactivity targeting resistant pathogens
Kratky, M., Konecna, K., Simkova, A., Jandourek, O., Maixnerova, J., Stolarikova, J., Vejsova, M., Voxova, B., Trejtnar, F., & Vinsova, J. (2023). Future Med Chem, 15(3), 255-274.
Insight into the Antibacterial Action of Iodinated Imine, an Analogue of Rafoxanide: a Comprehensive Study of Its Antistaphylococcal Activity
Kratky, M., Konecna, K., Jandourek, O., Diepoltova, A., Vavrova, P., Voxova, B., Vejsova, M., Barta, P., & Bosze, S. (2023). Microbiol Spectr, 11(3), e0306422.
The interactions between PML nuclear bodies and small and medium size DNA viruses
Ryabchenko, B., Sroller, V., Hornikova, L., Lovtsov, A., Forstova, J., & Huerfano, S. (2023). Virol J, 20(1), 82.
Clostridioides difficile infections were predominantly driven by fluoroquinolone-resistant Clostridioides difficile ribotypes 176 and 001 in Slovakia in 2018-2019
Plankaova, A., Brajerova, M., Capek, V., Balikova Novotna, G., Kinross, P., Skalova, J., Soltesova, A., Drevinek, P., & Krutova, M. (2023). Int J Antimicrob Agents, 62(1), 106824.
Epidemiology of Methicillin-Resistant Staphylococcus aureus in Slovakia, 2020 – Emergence of an Epidemic USA300 Clone in Community and Hospitals
Tkadlec, J., Le, A. V., Brajerova, M., Soltesova, A., Marcisin, J., Drevinek, P., & Krutova, M. (2023). Microbiol Spectr, 11(4), e0126423.
An emerging Panton-Valentine leukocidin-positive CC5-meticillin-resistant Staphylococcus aureus-IVc clone recovered from hospital and community settings over a 17-year period from 12 countries investigated by whole-genome sequencing
Aloba, B. K., Kinnevey, P. M., Monecke, S., Brennan, G. I., O’Connell, B., Blomfeldt, A., McManus, B. A., Schneider-Brachert, W., Tkadlec, J., Ehricht, R., Senok, A., Bartels, M. D., & Coleman, D. C. (2023). J Hosp Infect, 132, 8-19.
To screen or not to screen medical students for carriage of multidrug-resistant pathogens?
Smelikova, E., Drevinek, P., Nyc, O., Brajerova, M., Tkadlec, J., & Krutova, M. (2023). J Hosp Infect, 140, 15-23.
Direct 16S/18S rRNA Gene PCR Followed by Sanger Sequencing as a Clinical Diagnostic Tool for Detection of Bacterial and Fungal Infections: a Systematic Review and Meta-Analysis
Drevinek, P., Hollweck, R., Lorenz, M. G., Lustig, M., & Bjarnsholt, T. (2023). J Clin Microbiol, 61(9), e0033823.
Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity: a randomised, double-blinded placebo-controlled clinical trial
Jenickova, E., Andren Aronsson, C., Mascellani Bergo, A., Cinek, O., Havlik, J., & Agardh, D. (2023). Front Nutr, 10, 1183963.
Faecal bacteriome and metabolome profiles associated with decreased mucosal inflammatory activity upon anti-TNF therapy in paediatric Crohn’s disease.
Hurych, J., Mascellani Bergo, A., Lerchova, T., Hlinakova, L., Kubat, M., Malcova, H., Cebecauerova, D., Schwarz, J., Karaskova, E., Hecht, T., Vyhnanek, R., Toukalkova, L., Dotlacil, V., Greinerova, K., Cizkova, A., Horvath, R., Bronsky, J., Havlik, J., Hradsky, O., & Cinek, O. (2023). J Crohns Colitis.
University of Chemical Technology in Prague
Modulation of the bacterial virulence and resistance by well-known European medicinal herbs
Krizkovska, B., Hoang, L., Brdova, D., Klementova, K., Szemeredi, N., Louckova, A., Kronusova, O., Spengler, G., Kastanek, P., Hajslova, J., Viktorova, J., & Lipov, J. (2023). J Ethnopharmacol, 312, 116484.
Palacký University in Olomouc
Analysis of Bacterial Pathogens Causing Complicating HAP in Patients with Secondary Peritonitis.
Chudacek, J., Spicka, P., Kolar, M., Stasek, M., Kolcun, S., Klos, D., Hricova, K., Mlynarcik, P., Pudova, V., Klementova, O., & Horacek, R. (2023). Antibiotics (Basel), 12(3).
Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19.
Garmendia, J. V., Garcia, A. H., De Sanctis, C. V., Hajduch, M., & De Sanctis, J. B. (2022). Curr Issues Mol Biol, 45(1), 33-50.
Clinical microbiology and its role in current medicine
Kolar, M. (2023). Vnitr Lek, 69(E-1), 11-14.
[(68)Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography
Bendova, K., Raclavsky, V., Novotny, R., Luptakova, D., Popper, M., Novy, Z., Hajduch, M., & Petrik, M. (2023). J Med Chem, 66(11), 7584-7593.
Institute of Organic Chemistry and Biochemistry of the CAS, v. v. i.
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase
Silhan, J., Klima, M., Otava, T., Skvara, P., Chalupska, D., Chalupsky, K., Kozic, J., Nencka, R., & Boura, E. (2023). Nat Commun, 14(1), 2259.
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39
Skvara, P., Chalupska, D., Klima, M., Kozic, J., Silhan, J., & Boura, E. (2023). Antiviral Res, 216, 105663.
Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus
Zgarbova, M., Otava, T., Silhan, J., Nencka, R., Weber, J., & Boura, E. (2023). Antiviral Res, 218, 105714.
Structure of monkeypox virus poxin: implications for drug design
Duchoslav, V., & Boura, E. (2023). Arch Virol, 168(7), 192.
Detection of viable SARS-CoV-2 on the hands of hospitalized children with COVID-19.
Haas, M., Furhacker, P., Hodek, J., Stangl, P., Alon, I., Kainz, K., Fajgelj, V., Madel, C., Dotzler, S., Gotzinger, F., Ulrychova, L., Preuner, S., Fortschegger, M., Schinnerl, D., Walter, C., Obrova, K., Weber, J., Zacharasiewicz, A., & Lion, T. (2023). Clin Microbiol Infect, 29(9), 1211-1213.
Helquat dyes targeting G-quadruplexes as a new class of anti-HIV-1 inhibitors
Pavova, M., Reyes-Gutierrez, P. E., Kozak, J., Dobias, J., Yurenko, Y., Lepsik, M., Teply, F., & Weber, J. (2023). Sci Rep, 13(1), 6096.
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
Misehe, M., Matousova, M., Dvorakova, A., Hercik, K., Skach, K., Chalupska, D., Dejmek, M., Sala, M., Hajek, M., Boura, E., Mertlikova-Kaiserova, H., & Nencka, R. (2023). Eur J Med Chem, 260, 115717.
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
Stefek, M., Chalupska, D., Chalupsky, K., Zgarbova, M., Dvorakova, A., Krafcikova, P., Li, A. S. M., Sala, M., Dejmek, M., Otava, T., Chaloupecka, E., Kozak, J., Kozic, J., Vedadi, M., Weber, J., Mertlikova-Kaiserova, H., & Nencka, R. (2023). ACS Omega, 8(30), 27410-27418.
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy
Dejmek, M., Brazdova, A., Otava, T., Polidarova, M. P., Klima, M., Smola, M., Vavrina, Z., Budesinsky, M., Dracinsky, M., Liboska, R., Boura, E., Birkus, G., & Nencka, R. (2023). Eur J Med Chem, 259, 115685.
Institute of Molecular Genetics of the CAS, v. v. i.
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells
Horkova, V., Drobek, A., Paprckova, D., Niederlova, V., Prasai, A., Uleri, V., Glatzova, D., Kraller, M., Cesnekova, M., Janusova, S., Salyova, E., Tsyklauri, O., Kadlecek, T. A., Krizova, K., Platzer, R., Schober, K., Busch, D. H., Weiss, A., Huppa, J. B., & Stepanek, O. (2023). Nat Immunol, 24(1), 174-185.
Identification of GC-rich LAT genes in birds
Janusova, S., Krchlikova, V., Hron, T., Elleder, D., & Stepanek, O. (2023). PLoS One, 18(4), e0283431.
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
Tsyklauri, O., Chadimova, T., Niederlova, V., Kovarova, J., Michalik, J., Malatova, I., Janusova, S., Ivashchenko, O., Rossez, H., Drobek, A., Vecerova, H., Galati, V., Kovar, M., & Stepanek, O. (2023).
Bystander activation in memory and antigen-inexperienced memory-like CD8 T cells
Paprckova, D., Salyova, E., Michalik, J., & Stepanek, O. (2023). Curr Opin Immunol, 82, 102299.
Dynamic Evolution of Avian RNA Virus Sensors: Repeated Loss of RIG-I and RIPLET
Krchlikova, V., Hron, T., Tesicky, M., Li, T., Ungrova, L., Hejnar, J., Vinkler, M., & Elleder, D. (2022). Viruses, 15(1).
Unraveling the palindromic and nonpalindromic motifs of retroviral integration site sequences by statistical mixture models
Miklik, D., Grim, J., Elleder, D., & Hejnar, J. (2023). Genome Res, 33(8), 1395-1408.
Independent loss events of a functional tetherin gene in galliform birds
Krchlikova, V., Lotke, R., Haussmann, I., Reinisova, M., Kucerova, D., Pecnova, L., Ungrova, L., Hejnar, J., Sauter, D., & Elleder, D. (2023). J Virol, e0080323.
Institute of Microbiology of the CAS, v. v. i.
Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment
Farman, M. R., Petrackova, D., Kumar, D., Drzmisek, J., Saha, A., Curnova, I., Capek, J., Hejnarova, V., Amman, F., Hofacker, I., & Vecerek, B. (2023). Emerg Microbes Infect, 12(1), e2146536.
Healthy microbiome – a mere idea or a sound concept?
Najmanova, L., Videnska, P., & Cahova, M. (2022). Physiol Res, 71(6), 719-738.
What the Hel: recent advances in understanding rifampicin resistance in bacteria
Sudzinova, P., Sanderova, H., Koval, T., Skalova, T., Borah, N., Hnilicova, J., Kouba, T., Dohnalek, J., & Krasny, L. (2022). FEMS Microbiol Rev.
BopN is a Gatekeeper of the Bordetella Type III Secretion System
Navarrete, K. M., Bumba, L., Prudnikova, T., Malcova, I., Allsop, T. R., Sebo, P., & Kamanova, J. (2023). Microbiol Spectr, 11(3), e0411222.
Characterization of a transitionally occupied state and thermal unfolding of domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis
Tuzincin, D., Padrta, P., Sanderova, H., Rabatinova, A., Bendova, K., Krasny, L., Zidek, L., & Kaderavek, P. (2023). Proteins, 91(9), 1276-1287.
A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin-independent cell penetration
Osickova, A., Knoblochova, S., Bumba, L., Man, P., Kalaninova, Z., Lepesheva, A., Jurnecka, D., Cizkova, M., Biedermannova, L., Goldsmith, J. A., Maynard, J. A., McLellan, J. S., Osicka, R., Sebo, P., & Masin, J. (2023). J Biol Chem, 299(8), 104978.
The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity
Chen, G., Wang, H., Bumba, L., Masin, J., Sebo, P., & Li, H. (2023). J Biol Chem, 299(9), 105150.
The alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic
Burton, A. T., Pospisilova, D., Sudzinova, P., Snider, E. V., Burrage, A. M., Krasny, L., & Kearns, D. B. (2023). J Bacteriol, e0011223.
Structure-Function Analysis of the S-Glycosylation Reaction in the Biosynthesis of Lincosamide Antibiotics
Mori, T., Sun, X., Kadlcik, S., Janata, J., & Abe, I. (2023). Angew Chem Int Ed Engl, 62(29), e202304989
Molecular basis for carrier protein-dependent amide bond formation in the biosynthesis of lincosamide antibiotics
Mori, T., Kadlcik, S., Lyu, S., Kamenik, Z., Sakurada, K., Mazumdar, A., Wang, H., Janata, J., & Abe, I. (2023). Nature Catalysis, 1-12.
Biological Centre of the CAS, v. v. i.
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
Bianchini, F., Crivelli, V., Abernathy, M. E., Guerra, C., Palus, M., Muri, J., Marcotte, H., Piralla, A., Pedotti, M., De Gasparo, R., Simonelli, L., Matkovic, M., Toscano, C., Biggiogero, M., Calvaruso, V., Svoboda, P., Cervantes Rincon, T., Fava, T., Podesvova, L., . . . Robbiani, D. F. (2023). Sci Immunol, 8(81), eade0958.
Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation
Strakova, P., Bednar, P., Kotoucek, J., Holoubek, J., Fortova, A., Svoboda, P., Stefanik, M., Huvarova, I., Simeckova, P., Masek, J., Gvozdev, D. A., Mikhnovets, I. E., Chistov, A. A., Nikitin, T. D., Krasilnikov, M. S., Ustinov, A. V., Alferova, V. A., Korshun, V. A., Ruzek, D., & Eyer, L. (2023). Virus Res, 334, 199158.
Membrane-Targeting Perylenylethynylphenols Inactivate Medically Important Coronaviruses via the Singlet Oxygen Photogeneration Mechanism
Mariewskaya, K. A., Gvozdev, D. A., Chistov, A. A., Strakova, P., Huvarova, I., Svoboda, P., Kotoucek, J., Ivanov, N. M., Krasilnikov, M. S., & Zhitlov, M. Y. (2023). Molecules, 28(17), 6278.
The Influence of Adjuvant Type on the Immunogenicity of RBD/N Cocktail Antigens as a Vaccine Candidate against SARS-CoV-2 Virus
Brzuska, G., Zimna, M., Baranska, K., Szewczyk, B., Strakova, P., Ruzek, D., & Krol, E. (2023). Microbiol Spectr, 11(3), e0256422.
A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody
Svoboda, P., Haviernik, J., Bednar, P., Matkovic, M., Cervantes Rincon, T., Keeffe, J., Palus, M., Salat, J., Agudelo, M., Nussenzweig, M. C., Cavalli, A., Robbiani, D. F., & Ruzek, D. (2023). Cell Rep, 42(9), 113149.
Efficacy and immunogenicity of a veterinary vaccine candidate against tick-borne encephalitis in dogs.
Salat, J., Hunady, M., Svoboda, P., Strelcova, L., Strakova, P., Fortova, A., Palus, M., & Ruzek, D. (2023). Vaccine, 41(42), 6150-6155.
